张曼,女,汉族,中共党员,博士,讲师。1990年5月出生于辽宁省沈阳市,2019年7月毕业于内蒙古农业大学兽医学院基础兽医学专业(动物解剖学方向),随后到河南牧业经济学院动物医药学院基础兽医教研室工作,主要讲授《动物解剖学》和《动物组织学与胚胎学》等课程。研究领域为动物消化道黏膜免疫,先后主持并完成河南省青年基金项目1项、河南省科技攻关项目2项、河南省高等学校重点科研项目1项,以第一作者在《Ecotoxicology and environmental safety》、《Cellular Signalling》和《BMC veterinaryresearch》等高水平杂志发表研究论文6篇,获河南省科技优秀论文二等奖1项;主持及参与河南省教学工程质量和校级教改项目各1项,发表教研论文2篇,主编、参编教材3部,并于2024年荣获校级“文明教师”称号。
代表性成果:
1.Zhang Man, Li Qinghao, Wang Jun, Sun Juan, Xiang Yuqiang, Jin Xin*. Aflatoxin B1 disrupts the intestinal barrier integrity by reducing junction protein and promoting apoptosis in pigs and mice.Ecotoxicology and environmental safety. 2022, 247: 114250.(6.8/中科院1区)
2.Jin X, Li QH, Sun J,Zhang M, Xiang YQ. Porcine β-defensin-2 alleviates AFB1-induced intestinal mucosal injury by inhibiting oxidative stress and apoptosis.Ecotoxicology and environmental safety. 2023, 262:115161.(共同通讯)(6.8/中科院1区)
3.Zhang Man, Jin Xin, Yang Yin-feng*, Cao-gui-fang*. β-glucans from Saccharomyces cerevisiae are involved in immunostimulation of ovine ruminal explants. Canadian journal of veterinary research.2020, 84(4): 283-293.(IF:1.31/中科院4区)。
4.Zhang Man, Jin Xin, Yang Yin-feng*. β-glucan from Saccharomyces cerevisiae induces SBD-1 production in ovine ruminal epithelial cells via the Dectin-1- Syk- NF-κB signaling pathway. Cellular Signalling, 2019, 53: 304-315.(3.968/中科院2区)
5.Jin Xin,Zhang Man,Zhu Xue-min,Fan Yan-ru,Du Chen-guang,Bao Hua-er,Xu Siri-guleng,Tian Qiao-zhen,Wang Yun-he,Yang Yin-feng*. Modulation of ovine SBD-1 expression by Saccharomyces cerevisiae in ovine ruminal epithelial cells. BMC veterinary research. 2018, 14(1): 134.(并列第一)(1.792/中科院2区)